TRANS METHYL O-BENZYL-L-4-HYDROXYPROLINE
TRANS METHYL O-BENZYL-L-4-HYDROXYPROLINE
CAS: 113490-76-9
Molecular Formula: C13H17NO3
TRANS METHYL O-BENZYL-L-4-HYDROXYPROLINE - Names and Identifiers
| Name | TRANS METHYL O-BENZYL-L-4-HYDROXYPROLINE |
| Synonyms | methyl (4R)-4-(benzyloxy)-L-prolinate TRANS METHYL O-BENZYL-L-4-HYDROXYPROLINE L-Proline, 4-(phenylmethoxy)-, methyl ester, (4R)- trans-Methyl 4-(benzyloxy)pyrrolidine-2-carboxylate (2S,4R)-Methyl 4-(benzyloxy)pyrrolidine-2-carboxylate Methyl (2S,4R)-4-(benzyloxy)pyrrolidine-2-carboxylate (2S,4R)-4-BENZYLOXY-PYRROLIDINE-2-CARBOXYLIC ACID METHYL ESTER |
| CAS | 113490-76-9 |
| InChI | InChI=1/C13H17NO3/c1-16-13(15)12-7-11(8-14-12)17-9-10-5-3-2-4-6-10/h2-6,11-12,14H,7-9H2,1H3/t11-,12+/m1/s1 |
TRANS METHYL O-BENZYL-L-4-HYDROXYPROLINE - Physico-chemical Properties
| Molecular Formula | C13H17NO3 |
| Molar Mass | 235.28 |
| Density | 1.14±0.1 g/cm3(Predicted) |
| Melting Point | 124-125 °C |
| Boling Point | 331.6±42.0 °C(Predicted) |
| Flash Point | 154.3°C |
| Vapor Presure | 0.000154mmHg at 25°C |
| pKa | 7.23±0.10(Predicted) |
| Refractive Index | 1.54 |
TRANS METHYL O-BENZYL-L-4-HYDROXYPROLINE - Introduction
Methyl (2S,4R)-N-BOC-4-benzyloxy-2-pyrrolidinecarboxylate is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: colorless liquid
-Molecular formula: C15H21NO4
-Molecular weight: 283.33g/mol
-melting point: 58-60 ℃
-Boiling Point: 115-116 ℃(0.3 mmHg)
Use:
- (2S,4R)-N-BOC-4-benzyloxy-2-pyrrolidinecarboxylic acid methyl ester is commonly used as a reagent and intermediate in organic synthesis reactions.
-It can be used to synthesize biologically active compounds and drugs.
-It may be used as a precursor for anti-cancer and anti-viral drugs in drug research.
Preparation Method:
(2S,4R)-N-BOC-4-benzyloxy-2-pyrrolidine carboxylic acid methyl ester is prepared as follows:
1. The (2S,4R)-4-benzyloxy-2-pyrrolic acid methyl ester reacts with a N-BOC protecting agent to generate the corresponding N-BOC protected compound.
2. through the esterification reaction under alkali catalysis, it reacts with methanol to generate (2S,4R)-N-BOC-4-benzyloxy-2-pyrrolidine methyl ester.
Safety Information:
Methyl- (2S,4R)-N-BOC-4-benzyloxy-2-pyrrolidinecarboxylate is an organic compound and should be avoided by inhalation, swallowing and skin contact.
-Wear appropriate personal protective equipment such as lab gloves, goggles and lab coats when used.
-Chemical safety practices should be followed during storage and handling.
-In case of accidental contact or misuse, seek medical advice immediately and bring details of the compound.
Nature:
-Appearance: colorless liquid
-Molecular formula: C15H21NO4
-Molecular weight: 283.33g/mol
-melting point: 58-60 ℃
-Boiling Point: 115-116 ℃(0.3 mmHg)
Use:
- (2S,4R)-N-BOC-4-benzyloxy-2-pyrrolidinecarboxylic acid methyl ester is commonly used as a reagent and intermediate in organic synthesis reactions.
-It can be used to synthesize biologically active compounds and drugs.
-It may be used as a precursor for anti-cancer and anti-viral drugs in drug research.
Preparation Method:
(2S,4R)-N-BOC-4-benzyloxy-2-pyrrolidine carboxylic acid methyl ester is prepared as follows:
1. The (2S,4R)-4-benzyloxy-2-pyrrolic acid methyl ester reacts with a N-BOC protecting agent to generate the corresponding N-BOC protected compound.
2. through the esterification reaction under alkali catalysis, it reacts with methanol to generate (2S,4R)-N-BOC-4-benzyloxy-2-pyrrolidine methyl ester.
Safety Information:
Methyl- (2S,4R)-N-BOC-4-benzyloxy-2-pyrrolidinecarboxylate is an organic compound and should be avoided by inhalation, swallowing and skin contact.
-Wear appropriate personal protective equipment such as lab gloves, goggles and lab coats when used.
-Chemical safety practices should be followed during storage and handling.
-In case of accidental contact or misuse, seek medical advice immediately and bring details of the compound.
Last Update：2024-04-09 02:00:41
